Malegra DXT is a combination medication that is used to treat two sexual disorders in men: erectile dysfunction (ED) and premature ejaculation (PE). It contains two active ingredients: Sildenafil citrate and Duloxetine.

Sildenafil Citrate: This is a phosphodiesterase type 5 (PDE5) inhibitor, the same active ingredient found in medications like Viagra. It helps increase blood flow to the penis, aiding in achieving and maintaining an erection during sexual stimulation.

Duloxetine: This is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI) used to treat conditions like depression and anxiety. In Malegra DXT, it is used to address premature ejaculation by delaying ejaculation and extending the time before orgasm occurs during sexual activity.

The duration of effect for Malegra DXT can vary based on individual factors, including metabolism, dosage, and other health conditions. Generally, Sildenafil's effect can last around 4 to 6 hours, during which you may experience improved erectile function and the ability to have satisfactory sexual intercourse. The effects of Duloxetine on premature ejaculation can vary, but it is designed to help extend the time to ejaculation.

It's important to note that the effectiveness and duration of Malegra DXT may differ from person to person. Additionally, the medication may have potential side effects and interactions with other drugs, so it's crucial to use it under the guidance of a healthcare provider. They can provide personalized advice, including information about the expected duration of effect and any other considerations related to using Malegra DXT.