Jill Browwn
Guest
Aug 06, 2024
11:52 PM
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1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride ( EDC HCl ) is a chemical reagent commonly used in biochemistry and molecular biology for the activation of carboxyl groups in peptides, proteins, and nucleic acids. Here's a detailed description:
Chemical Structure and Properties:
• IUPAC Name: 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride
• Chemical Formula: C8H17N3 · HCl
• Molecular Weight: 191.70 g/mol (without HCl), 190.70 g/mol (with HCl)
• Appearance: White crystalline powder
• Solubility: Soluble in water and most organic solvents like ethanol, methanol, and DMF (dimethylformamide)
• Melting Point: Approximately 110-115°C (decomposition)
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