Ronymeran
Guest
Sep 26, 2024
12:44 AM
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Fildena 120 mg is a medication primarily used to treat erectile dysfunction (ED) in men. It contains Sildenafil Citrate as its active ingredient, a well-known phosphodiesterase type 5 (PDE5) inhibitor. Understanding how Fildena works can help users effectively manage their ED and improve their sexual health.
1. Mechanism of Action
Fildena 120 mg works by enhancing blood flow to the penis during sexual arousal. Here’s a detailed look at its mechanism:
Inhibition of PDE5: In a healthy male, sexual arousal leads to the release of nitric oxide (NO) in the penis. Nitric oxide stimulates the production of cyclic guanosine monophosphate (cGMP), a molecule that relaxes the smooth muscles of blood vessels, allowing increased blood flow. However, an enzyme called phosphodiesterase type 5 (PDE5) can break down cGMP, reducing its effectiveness.
Increased cGMP Levels: Fildena 120 mg inhibits the action of PDE5, preventing it from degrading cGMP. As a result, cGMP levels remain elevated, promoting prolonged relaxation of the smooth muscle and vasodilation (widening of blood vessels).
Enhanced Blood Flow: The increased blood flow to the penis helps achieve and maintain an erection in response to sexual stimulation. This process allows men to engage in sexual activity more confidently and effectively.
2. Onset of Action and Duration
Onset: Fildena 120 mg typically takes about 30 to 60 minutes to start working. However, this can vary based on individual factors, including metabolism and the presence of food in the stomach.
Duration: The effects of Fildena can last for approximately 4 to 6 hours, allowing for multiple opportunities for sexual activity during this time. However, stimulation is necessary for an erection to occur; Fildena does not automatically cause an erection without sexual arousal.
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