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Massachusetts Fishing Reports > Why does Vigora 50 Mg interact with nitrates?
Why does Vigora 50 Mg interact with nitrates?
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cliffordfosterr
Guest
Mar 06, 2025
1:38 AM
Vigora 50 mg, which contains sildenafil, is a medication used to treat erectile dysfunction. It interacts with nitrates because both drugs have similar effects on the body’s blood vessels. Vigora 50mg works by inhibiting an enzyme (PDE5), which relaxes blood vessels and improves blood flow, particularly in the penis.

Nitrates, commonly used to treat chest pain or angina, also relax blood vessels by increasing nitric oxide levels. When taken together, the combined effect can lead to a dangerous drop in blood pressure, which can result in dizziness, fainting, heart attack, or stroke. Therefore, the combination of Vigora and nitrates is contraindicated for safety reasons.


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