Guest
Guest
Dec 26, 2025
10:29 PM
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Fildena 50 mg contains sildenafil citrate, a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). Its absorption and effectiveness depend on how it is processed in the body.
After oral administration, FILDENA 50 MG is rapidly absorbed from the gastrointestinal tract. The onset of action typically occurs within 30–60 minutes, although peak plasma concentrations are usually reached around 1 hour after ingestion. Absorption can be affected by food intake; a high-fat meal may delay the onset and reduce the speed of absorption, though the overall effectiveness remains largely unchanged.
Once absorbed, sildenafil is distributed throughout the body via the bloodstream. It works by inhibiting the PDE5 enzyme, which increases cyclic GMP (cGMP) levels in the smooth muscles of penile blood vessels. This leads to relaxation of the vessels, allowing increased blood flow into the penis during sexual stimulation.
Fildena is metabolized primarily in the liver by the CYP3A4 enzyme system. Its breakdown produces metabolites that are largely inactive. The drug and its metabolites are eliminated mainly through the feces and urine, with an average half-life of approximately 4 hours, meaning that the active effect gradually declines over this period.
Fildena 50 mg is quickly absorbed in the gastrointestinal tract, especially on an empty stomach, reaches peak levels in about an hour, and works by enhancing blood flow in the penis. Its metabolism and excretion ensure that the drug’s effects are temporary and predictable, allowing controlled use under medical supervision.
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