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Massachusetts Fishing Reports > Why does Filitra 40 Mg cause muscle aches ?
Why does Filitra 40 Mg  cause muscle aches  ?
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Jan 12, 2026
11:31 PM
Filitra 40 mg contains Vardenafil, a PDE5 inhibitor used to treat erectile dysfunction (ED). Like other PDE5 inhibitors (sildenafil, tadalafil), it works by relaxing blood vessels to increase blood flow to the penis. However, this mechanism can sometimes lead to muscle aches and body pains in certain individuals. Why Muscle Aches Happen Vasodilation Effects Vardenafil relaxes smooth muscles in blood vessels throughout the body, not just in the penis. This widespread muscle relaxation can cause Filitra 40 Mg tension changes or cramps in skeletal muscles, especially in the back, neck, or shoulders. Nitric Oxide Pathway PDE5 inhibitors increase nitric oxide (NO) levels in tissues, which helps relax blood vessels. NO also affects muscle fibers, sometimes causing transient soreness or stiffness. Changes in Blood Flow Increased circulation can occasionally lead to temporary muscle fatigue or mild aches, especially in men who are less physically active or have underlying musculoskeletal conditions. Individual Sensitivity Some men are more sensitive to PDE5 inhibitors, so even a normal dose like 40 mg can trigger mild myalgia (muscle pain). How Long It Lasts Muscle aches usually appear within 12–24 hours of taking Filitra and typically resolve within 1–2 days. Over-the-counter pain relievers like paracetamol or gentle stretching can help. When to See a Doctor If muscle pain is severe, persistent, or accompanied by chest pain, vision changes, or priapism, seek medical attention immediately. Men with liver, kidney, or heart conditions should consult a doctor before using Filitra.


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