Guest
Guest
Aug 24, 2026
7:52 PM
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Engineered B cell is a potential technique for tumor treatment by expressing and carrying therapeutic proteins to the target site. To make it a long-lived delivery cell like plasma cells that can live in the bone marrow microenvironment for decades and secrete high-affinity antigen-specific antibodies to combat pathogens. One of the approaches is to guide B cell lineage transit to the plasma cell, as the plasma cell is one of the terminally differentiated cells of B cells and may be acquired by multiple approaches recapitulating the B cell differentiation process in vivo.
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